Anti-SSB Polyclonal Antibody
Cat: K000327P
Summary:
| 【Product name】：Anti-SSB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6741 | 【Swiss Prot】：P05455 |
| 【Tested applications】：IHC,WB,IP,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:100-500. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human SSB | |
| 【Public Immunogen Range】：166-408aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
Verified picture:
Western blot analysis with SSB antibody diluted at 1:700;Lane: Jurkat LO2 HepG2 293T.
Immunohistochemistry of paraffin-embedded human breast cancer with SSB antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using SSB antibody diluted at 1:100.