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Anti-ELAVL1 Polyclonal Antibody
Cat: K000351P
Summary:
【Product name】:Anti-ELAVL1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1994 【Swiss Prot】:Q15717
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human ELAVL1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain using ELAVL1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using ELAVL1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF7 cell using ELAVL1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with ELAVL1 antibody diluted at 1:1000;Lane: U-251MG HeLa Jurkat K-562 PC-3.
Immunohistochemistry of paraffin-embedded mouse testis with ELAVL1 antibody diluted at 1:150.