Anti-ELAVL1 Polyclonal Antibody
Cat: K000351P
Summary:
| 【Product name】：Anti-ELAVL1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1994 | 【Swiss Prot】：Q15717 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:100-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ELAVL1 | |
| 【Public Immunogen Range】：1-326aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain using ELAVL1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using ELAVL1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF7 cell using ELAVL1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with ELAVL1 antibody diluted at 1:1000;Lane: U-251MG HeLa Jurkat K-562 PC-3.
Immunohistochemistry of paraffin-embedded mouse testis with ELAVL1 antibody diluted at 1:150.