下载
Anti-CPT1A Polyclonal Antibody - SAlexa Fluor 594
Cat: K000391P - SAlexa Fluor 594
Summary:
【Product name】:Anti-CPT1A Polyclonal Antibody - SAlexa Fluor 594 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1374 【Swiss Prot】:P50416
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CPT1A
【Public Immunogen Range】:520-720aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture: