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Anti-PUM1 Polyclonal Antibody
Cat: K000420P
Summary:
【Product name】:Anti-PUM1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:9698 【Swiss Prot】:Q14671
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human PUM1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
Verified picture:
Western blot analysis with PUM1 antibody diluted at 1:1000