Anti-IRAK4 Polyclonal Antibody
Cat: K000423P
Summary:
| 【Product name】：Anti-IRAK4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51135 | 【Swiss Prot】：Q9NWZ3 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-200.IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IRAK4 | |
| 【Public Immunogen Range】：1-220aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using IRAK4 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with IRAK4 antibody diluted at 1:1000;Lane: Rat lung.
Immunohistochemistry of paraffin-embedded rat spleen with IRAK4 antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using IRAK4 antibody diluted at 1:100.