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Anti-SMAD3 Polyclonal Antibody
Cat: K000497P
Summary:
【Product name】:Anti-SMAD3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4088 【Swiss Prot】:P84022
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IHC,WB,ELISA
【Immunogen】:Recombinant Protein
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.
Verified picture:
Immunohistochemistry of paraffin-embedded human breast caricnoma using SMAD3 antibody diluted at 1:500.
Western blot analysis with SMAD3 antibody diluted at 1:2000;Lane: A431,HeLa,C2C12,3T3,PC12,Rat Brain.