Anti-CANX Polyclonal Antibody
Cat: K000499P
Summary:
| 【Product name】：Anti-CANX Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：821 | 【Swiss Prot】：P27824 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-2000. IHC 1:200-500. | |
| 【Immunogen】：Recombinant Protein | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.
Verified picture:
Western blot analysis with CANX antibody diluted at 1:2000, lane1-3: Hela, 3T3, PC12
Immunohistochemistry of paraffin-embedded Human Breast Carcinoma with CANX antibody diluted at 1:500