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Anti-HK1 Monoclonal Antibody - SAlexa Fluor 532
Cat: K001388M - SAlexa Fluor 532
Summary:
【Product name】:Anti-HK1 Monoclonal Antibody - SAlexa Fluor 532 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:3098 【Swiss Prot】:P19367
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human HK1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. (provided by RefSeq, Apr 2009).
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