This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family.Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes,whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms.The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,and a pseudogene of this gene is located on the long arm of chromosome 5.[provided by RefSeq,Dec 2011]