Anti-KEAP1 Polyclonal Antibody - HRP
Cat: K001511P - HRP
Summary:
| 【Product name】：Anti-KEAP1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9817 | 【Swiss Prot】：Q14145 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human KEAP1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
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