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Anti-SPHK1 Polyclonal Antibody - Cy5
Cat: K001579P - Cy5
Summary:
【Product name】:Anti-SPHK1 Polyclonal Antibody - Cy5 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:8877 【Swiss Prot】:Q9NYA1
【Species reactivity】:Human,Mouse
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human SPHK1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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