Anti-HDAC4 Polyclonal Antibody
Cat: K001584P
Summary:
| 【Product name】：Anti-HDAC4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9759 | 【Swiss Prot】：P56524 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human HDAC4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain using HDAC4 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with HDAC4 antibody diluted at 1:700;Lane: HepG2 Mouse brain.
Immunohistochemistry of paraffin-embedded human stomach with HDAC4 antibody diluted at 1:75.