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Anti-PRKCA Polyclonal Antibody
Cat: K001644P
Summary:
【Product name】:Anti-PRKCA Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5578 【Swiss Prot】:P17252
【Species reactivity】:Rat,Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human PRKCA
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Verified picture:
Immunohistochemistry of paraffin-embedded lung cancer��hu�� using PRKCA antibody at dilution of 1:100 (x40 lens).
Western blot analysis with PRKCA antibody diluted at 1:1000;Lane: NIH3T3 Jurkat C6 SH-SY5Y Mouse brain Rat brain.