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Anti-NEDD4 Polyclonal Antibody - SAlexa Fluor 647
Cat: K001700P - SAlexa Fluor 647
Summary:
【Product name】:Anti-NEDD4 Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4734 【Swiss Prot】:P46934
【Species reactivity】:Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human NEDD4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
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