Anti-EDN1 Polyclonal Antibody
Cat: K001725P
Summary:
| 【Product name】：Anti-EDN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1906 | 【Swiss Prot】：P05305 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human EDN1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded human stomach using EDN1 antibody at dilution of 1:100 (40x lens).
Western blot analysis with EDN1 antibody diluted at 1:1000;Lane: BxPC-3 Rat heart.
Immunofluorescence analysis of NIH3T3 cells using EDN1 antibody diluted at 1:100.