Anti-SOCS3 Polyclonal Antibody
Cat: K001749P
Summary:
| 【Product name】：Anti-SOCS3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9021 | 【Swiss Prot】：O14543 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：A synthetic peptide of human SOCS3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Verified picture:
Western blot analysis with SOCS3 antibody diluted at 1:1000;Lane: Mouse brain Mouse thymus Rat liver.
Immunofluorescence analysis of NIH3T3 cells using SOCS3 antibody diluted at 1:100.