Anti-GAD2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K001778P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-GAD2 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2572 | 【Swiss Prot】：Q05329 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human GAD2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
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