Anti-PDE1A Polyclonal Antibody - Biotin
Cat: K002006P - Biotin
Summary:
| 【Product name】：Anti-PDE1A Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5136 | 【Swiss Prot】：P54750 |
| 【Species reactivity】：Rat,Mouse | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PDE1A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).
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