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Anti-PHGDH Polyclonal Antibody - SAlexa Fluor 640
Cat: K002010P - SAlexa Fluor 640
Summary:
【Product name】:Anti-PHGDH Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:26227 【Swiss Prot】:O43175
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:IP,IF,WB
【Immunogen】:Recombinant protein of human PHGDH
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
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