Anti-NFKBIA Polyclonal Antibody
Cat: K002147P
Summary:
| 【Product name】：Anti-NFKBIA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4792 | 【Swiss Prot】：P25963 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human NFKBIA | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Verified picture:
Western blot analysis with NFKBIA antibody diluted at 1:1000;Lane: MCF7 DU145 THP-1 A549 PC-3 Mouse spleen.
Immunofluorescence analysis of HeLa cells using NFKBIA antibody diluted at 1:50.