Anti-APEX1 Polyclonal Antibody
Cat: K002150P
Summary:
| 【Product name】：Anti-APEX1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：328 | 【Swiss Prot】：P27695 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human APEX1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Verified picture:
Western blot analysis with APEX1 antibody diluted at 1:1000;Lane: HeLa HepG2.
Immunofluorescence analysis of HeLa cells using APEX1 antibody diluted at 1:100.