Anti-POLR2A Polyclonal Antibody
Cat: K002155P
Summary:
| 【Product name】：Anti-POLR2A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5430 | 【Swiss Prot】：P24928 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：ChIP,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human POLR2A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Verified picture:
Western blot analysis with POLR2A antibody diluted at 1:1000;Lane: U-251MG Mouse liver Mouse brain.
Immunohistochemistry of paraffin-embedded human esophageal with POLR2A antibody diluted at 1:100.