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Anti-Casp8 Polyclonal Antibody - SAlexa Fluor 640
Cat: K002200P - SAlexa Fluor 640
Summary:
【Product name】:Anti-Casp8 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:12370 【Swiss Prot】:O89110
【Species reactivity】:Human,Mouse
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of mouse Casp8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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