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Anti-IRF3 Polyclonal Antibody
Cat: K002217P
Summary:
【Product name】:Anti-IRF3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3661 【Swiss Prot】:Q14653
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human IRF3
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Western blot analysis with IRF3 antibody diluted at 1:1000;Lane: THP-1 HT-29.
Immunofluorescence analysis of THP-1 cells using IRF3 antibody diluted at 1:100.