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Anti-ALDOA Polyclonal Antibody
Cat: K002233P
Summary:
【Product name】:Anti-ALDOA Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:226 【Swiss Prot】:P04075
【Species reactivity】:Mouse,Human
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human ALDOA
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Verified picture:
Western blot analysis with ALDOA antibody diluted at 1:1000;Lane: MCF7 DU145 293T HepG2 Jurkat A549 CEM Mouse skeletal muscle Mouse kidney.
Immunofluorescence analysis of A549 cells using ALDOA antibody diluted at 1:50.