Anti-TRADD Polyclonal Antibody
Cat: K002245P
Summary:
| 【Product name】：Anti-TRADD Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：71609 | 【Swiss Prot】：Q3U0V2 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of mouse TRADD | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Verified picture:
Immunohistochemistry of paraffin-embedded rat lung using TRADD antibody at dilution of 1:100.
Western blot analysis with TRADD antibody diluted at 1:1000;Lane: MCF7 Jurkat.