下载
Anti-H2AFX Polyclonal Antibody
Cat: K002285P
Summary:
【Product name】:Anti-H2AFX Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3014 【Swiss Prot】:P16104
【Species reactivity】:Mouse,Rat,Other (Wide Range),Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human H2AFX
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Verified picture:
Western blot analysis with H2AFX antibody diluted at 1:700;Lane: K-562 HeLa Mouse testis Rat testis.
Immunohistochemistry of paraffin-embedded rat testis with H2AFX antibody diluted at 1:100.