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Anti-CHD4 Polyclonal Antibody
Cat: K002297P
Summary:
【Product name】:Anti-CHD4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1108 【Swiss Prot】:Q14839
【Species reactivity】:Rat,Human,Mouse
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human CHD4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with CHD4 antibody diluted at 1:1000;Lane: HeLa Jurkat 293T HT-1080.
Immunohistochemistry of paraffin-embedded Rat liver with CHD4 antibody diluted at 1:150.
Immunofluorescence analysis of C6 cells using CHD4 antibody diluted at 1:100.