Anti-PRKAA1 Polyclonal Antibody
Cat: K002500P
Summary:
| 【Product name】：Anti-PRKAA1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5562 | 【Swiss Prot】：Q13131 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：A synthetic peptide of human PRKAA1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Verified picture:
Immunofluorescence analysis of HELA cells using AMPKa1 antibody diluted at 1:100
Western blot analysis with PRKAA1 antibody diluted at 1:1000;Lane: Mouse liver Mouse brain Rat liver.