Anti-MYBPC3 Polyclonal Antibody - SAlexa Fluor 750
Cat: K002511P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-MYBPC3 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4607 | 【Swiss Prot】：Q14896 |
| 【Species reactivity】：Mouse,Rat | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human MYBPC3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
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