Anti-ATXN3 Polyclonal Antibody
Cat: K002547P
Summary:
| 【Product name】：Anti-ATXN3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4287 | 【Swiss Prot】：P54252 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human ATXN3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Verified picture:
Western blot analysis with ATXN3 antibody diluted at 1:1000;Lane: Mouse brain Mouse thymus Rat brain.
Immunohistochemistry of paraffin-embedded human esophageal cancer with ATXN3 antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using ATXN3 antibody diluted at 1:100.