Anti-IL17A Polyclonal Antibody
Cat: K002562P
Summary:
| 【Product name】：Anti-IL17A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3605 | 【Swiss Prot】：Q16552 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IHC,WB,IF | |
| 【Immunogen】：A synthetic peptide of human IL17A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Verified picture:
Western blot analysis with IL17A antibody diluted at 1:1000;Lane: Recombinant Human IL-17A Protein Mouse thymus.
Immunohistochemistry of paraffin-embedded mouse kidney using IL17A antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human tonsil with IL17A antibody diluted at 1:100.