下载
Anti-PSMD13 Polyclonal Antibody
Cat: K002579P
Summary:
【Product name】:Anti-PSMD13 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5719 【Swiss Prot】:Q9UNM6
【Species reactivity】:Rat,Human,Mouse
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human PSMD13
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
Verified picture:
Western blot analysis with PSMD13 antibody diluted at 1:1000;Lane: HeLa HepG2 SW620 Mouse liver Mouse testis Mouse skeletal muscle.
Immunofluorescence analysis of U2OS cells using PSMD13 antibody diluted at 1:100.