Anti-SET Polyclonal Antibody
Cat: K002585P
Summary:
| 【Product name】：Anti-SET Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6418 | 【Swiss Prot】：Q01105 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human SET | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded rat liver tissue using SET antibody at dilution of 1:100 (x40 lens).
Western blot analysis with SET antibody diluted at 1:1000;Lane: HeLa 293T BT-474 HL-60 NIH3T3 Mouse spleen.
Immunohistochemistry of paraffin-embedded rat kidney with SET antibody diluted at 1:100.