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Anti-TIA1 Polyclonal Antibody
Cat: K002593P
Summary:
【Product name】:Anti-TIA1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:7072 【Swiss Prot】:P31483
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human TIA1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Verified picture:
Western blot analysis with TIA1 antibody diluted at 1:1000;Lane: HeLa 293T Mouse brain Mouse thymus.
Immunohistochemistry of paraffin-embedded human tonsil with TIA1 antibody diluted at 1:100.