Anti-TYR Polyclonal Antibody
Cat: K002603P
Summary:
| 【Product name】：Anti-TYR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7299 | 【Swiss Prot】：P14679 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human TYR | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded rat heart using TYR antibody at dilution of 1:100.
Western blot analysis with TYR antibody diluted at 1:1000;Lane: Rat brain.