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Anti-HDAC3 Polyclonal Antibody - HRP
Cat: K002605P - HRP
Summary:
【Product name】:Anti-HDAC3 Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:8841 【Swiss Prot】:O15379
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IF,IHC,WB
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:A synthetic peptide of human HDAC3
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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