Anti-DKC1 Polyclonal Antibody
Cat: K002714P
Summary:
| 【Product name】：Anti-DKC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1736 | 【Swiss Prot】：O60832 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human DKC1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with DKC1 antibody diluted at 1:1000;Lane: HeLa 22Rv1 HepG2 MCF7 K-562.
Immunohistochemistry of paraffin-embedded human lung cancer with DKC1 antibody diluted at 1:75.
Immunofluorescence analysis of NIH3T3 cells using DKC1 antibody diluted at 1:100.