Anti-CBS Polyclonal Antibody
Cat: K002779P
Summary:
| 【Product name】：Anti-CBS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：875 | 【Swiss Prot】：P35520 |
| 【Species reactivity】：Human Mouse Rat | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human CBS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
Verified picture:
Western blot analysis with CBS antibody diluted at 1:1000;Lane: HepG2 293T HeLa MCF7 Mouse liver Rat liver Rat kidney.
Immunofluorescence analysis of rat liver using CBS antibody diluted at 1:100.