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Anti-COL5A1 Polyclonal Antibody
Cat: K002810P
Summary:
【Product name】:Anti-COL5A1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1289 【Swiss Prot】:P20908
【Species reactivity】:Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human COL5A1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded esophageal cancer(hu) using COL5A1 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with COL5A1 antibody diluted at 1:1000;Lane: Mouse lung.