Anti-CYBB Polyclonal Antibody - SAlexa Fluor 532
Cat: K002889P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-CYBB Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1536 | 【Swiss Prot】：P04839 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human CYBB | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Verified picture: