Anti-PAX3 Polyclonal Antibody
Cat: K002916P
Summary:
| 【Product name】：Anti-PAX3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5077 | 【Swiss Prot】：P23760 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human PAX3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Verified picture:
Immunofluorescence analysis of MCF7 cell using PAX3 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with PAX3 antibody diluted at 1:1000;Lane: 293T Rat testis.
Immunohistochemistry of paraffin-embedded human colon carcinoma with PAX3 antibody diluted at 1:100.