Anti-PAX3 Polyclonal Antibody - Cy5
Cat: K002916P - Cy5
Summary:
| 【Product name】：Anti-PAX3 Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5077 | 【Swiss Prot】：P23760 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PAX3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
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