Anti-CFL1 Polyclonal Antibody
Cat: K002937P
Summary:
| 【Product name】：Anti-CFL1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1072 | 【Swiss Prot】：P23528 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human CFL1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Verified picture:
Western blot analysis with CFL1 antibody diluted at 1:1000;Lane: HeLa A549 Jurkat 293T Mouse brain Mouse liver Mouse kidney Rat brain Rat ovary.