Anti-HMBS Polyclonal Antibody - Cy3
Cat: K002977P - Cy3
Summary:
| 【Product name】：Anti-HMBS Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3145 | 【Swiss Prot】：P08397 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human HMBS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
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