下载
Anti-LIG1 Polyclonal Antibody
Cat: K003040P
Summary:
【Product name】:Anti-LIG1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3978 【Swiss Prot】:P18858
【Species reactivity】:Mouse,Human
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human LIG1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunofluorescence analysis of MCF7 cell using LIG1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with LIG1 antibody diluted at 1:1000;Lane: 293T K-562.