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Anti-RAD9A Polyclonal Antibody
Cat: K003058P
Summary:
【Product name】:Anti-RAD9A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5883 【Swiss Prot】:Q99638
【Species reactivity】:Human,Rat
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human RAD9A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded rat liver using RAD9A antibody at dilution of 1:200.
Western blot analysis with RAD9A antibody diluted at 1:1000;Lane: BT-474 22Rv1 HepG2 MCF7.