Anti-TRIM21 Polyclonal Antibody
Cat: K003101P
Summary:
| 【Product name】：Anti-TRIM21 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6737 | 【Swiss Prot】：P19474 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IP,IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human TRIM21 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
Verified picture:
Immunohistochemistry of paraffin-embedded Cervical cancer(hu) using TRIM21 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with TRIM21 antibody diluted at 1:1000;Lane: Jurkat HeLa Rat lung.
Immunohistochemistry of paraffin-embedded mouse spinal cord with TRIM21 antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using TRIM21 antibody diluted at 1:50.