Anti-CDKN1C Polyclonal Antibody - Biotin
Cat: K003183P - Biotin
Summary:
| 【Product name】：Anti-CDKN1C Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1028 | 【Swiss Prot】：P49918 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CDKN1C | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
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