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Anti-CNTFR Polyclonal Antibody
Cat: K003463P
Summary:
【Product name】:Anti-CNTFR Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1271 【Swiss Prot】:P26992
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:WB
【Immunogen】:Recombinant protein of human CNTFR
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded pancreatic cancer(hu) using CNTFR antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with CNTFR antibody diluted at 1:1000;Lane: U-87MG HeLa Mouse brain Mouse heart Rat testis.